11. Toxicological Information
Route of Entry
Skin Contact X Skin Absorption Eye Contact X Inhalation X Ingestion X
Oral LD50 (rat): >5,000 mg/kg
Dermal LD50 (rabbit): >5,000 mg/kg
Inhalation LC50 (rat): 2.88 mg/L
Eye Irritation (rabbit): Severe Irritant
Skin Irritation (rabbit): Slight Irritant
Dermal Sensitization (guinea pig): Not a dermal sensitizer
Carcinogenicity
No
Mutagenicity
No
Teratogenicity
No
Reproductive toxicity
No
Synergistic products
No
Sensitization
No
Neurotoxicity
No
Target organs
Eyes and Skin
12. EcologicalCarcinogenic Effects
For Component: o-Phenylphenol
Ortho-phenylphenol and Sodium ortho-phenylphenol were tested in accordance with the EPA Final Guidance for Carcinogenic Risk. OPP and Na-
OPP were classified as “Not Likely to be Carcinogenic to Humans” based on no evidence of carcinogenic effects at the defined dose range of 200
mg/kg/day. At doses greater than 200 mg/kg/day, OPP and Na-OPP were classified as “Likely to be Carcinogenic to Humans” based on the presence
of urinary bladder tumors in rats and the presence of liver tumors in mice